SCNIR Newsletter

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1 Determining your ANC (Absolute Neutrophil Count) CBC ( ( FBC ) measures the levels of the three basic blood cells - white cells, red cells, and platelets. also known as a Full Blood Count ) A Complete Blood Count ercentage of neutrophils (shown in this listing as Polys) in your white blood count. (Absolute Neutrophil Count) measures the p ANC An multiply your white blood count (WBC) x total neutrophils (segmented neutrophils% + segmented bands%) x 10 = ANC. 1,000 is considered neutropenic and the Registry considers that an individual - A normal ANC is over 1,000. An ANC of 500 (or Reference Interval Reference Range) column: whose ANC is chronically less than 500 has Severe Chronic Neutropenia. shows the normal range for each measurement. Different Result column: shows counts that fall within the normal range. White blood cells: help protect you from infection. labs may use different ranges, Flag column (this marks items that are out of range): shows counts For this patient, the total white cell count is 2.0, your test results may be that are lower (“L”) or higher (“H”) than the normal range. which is low. slightly different, depending on where your results are processed. Red Blood Cells: Carry oxygen from your lungs to the rest of your body. To determine your ANC: Hemoglobin (Hb or Hgb): the part of the red Flag Units Reference Interval Test Result cell that carries the oxygen. CBC WITH DIFFERENTIAL 1. Find the WBC, 3 Hematocrit (HCT), is a measure of the amount 4.8 - 10.8 White Blood Count x 10 / 2.0L μ L the polys and bands of red blood cells in the blood. 6 4.70 - 6.10 4.34L x 10 Red Blood Count / L on your CBC. μ 2.0 WBC : the cells that form blood clots that Platelets 13.2L - 14.0 18.0 Hemoglobin g/dL stop bleeding. The platelet count for this Polys 14.8% % 42.0 Hematocrit 52.0 - 37.5L patient is normal. 5% Bands 3 Platelets 278 L 400 - / μ 130 x 10 2. Add the polys and Polys (also known as segs, segmented 43.0 - 65.0 14.8L Polys % neutrophils, neutrophils, granulocytes) are the bands. most numerous of our white blood cells. These 5 (14.8 + 5 = 19.8) % Bands are the first line of defense against infection, 3. Multiply the sum % 55.5H Lymphocytes 20.5 - 45.5 killing invaders of the body. of the polys and % 5.5 - 11.7 Monocytes 22H Bands (also known as stabs, segs or bands by the WBC. % 0.9 Eosinophils 1.7 - 2.9 segmented bands) are immature polys. They 19.8 x 2.0 = 39.6 also function to kill invaders of the body. % 1.0 Basophils 1.0 - 0.2 4. Multiply the 2.0 - 0.0 Atypical lymphs % product by 10. 0.0 or lymphocytes are white blood cells Lymphs 3 39.6 x 10 = 396 4.8 0.3L x 10 Polys (absolute) / μ L 2.2 - which assist in building immunity and include 3 B and T cells. Bands (absolute) 0.1 x 10 / μ L This person has an 3 , eosinophils basophils Monocyctes , and / 2.9 Lymphs (absolute) 1.1L x 10 - 1.3 μ L ANC of 396 roy invading bacteria and viruses. dest 3 0.8 - 0.3 μ / x 10 Monocytes (absolute) 0.4 L 3 Differential : part of the CBC that shows 0.0 x 10 0.0 - 0.2 Eosinophils (absolute) / L μ counts for the five main kinds of white 3 μ 0.0 / L 0.0 - Basophils (absolute) x 10 0.1 cells, either as percentages (the first 6 3 counts), or as the number of cells (the 0.0 Atypical lymphs (absolute) 0.0 - 2.0 μ / L x 10 second 6 counts). This patient has a lower count and a higher than poly than normal To calculate the ANC from absolute numbers the formula is: monocyte and count. lymph normal Absolute polys + Absolute bands multiplied by 1000 = ANC (0.3 + 0.1) x 1000 = 400

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